Cholesterol: Two numbers men should watch to reduce heart attack risk

A cardiologist identifies LDL and non-HDL cholesterol as the two key measures linked to artery plaque, and screening frequency depends on individual cardiovascular risk with higher-risk patients tested more often.

A cardiologist highlights two cholesterol measures most closely tied to artery plaque and heart risk. Cholesterol is a normal body substance but excess levels can lead to plaque buildup in arteries. The article reports that low-density lipoprotein (LDL) and non-high-density lipoprotein (non-HDL) are the primary numbers used to estimate atherosclerosis risk. Screening frequency is described as varying by a person's overall cardiovascular risk. Key points: - About 10 percent of Americans aged 20 and up are reported to have high cholesterol. - LDL measures cholesterol carried by particles most likely to stick to artery walls; non-HDL includes LDL, VLDL and other particles associated with plaque buildup. - Reported target ranges: LDL under 100 mg/dL for most people and under 55 mg/dL for higher-risk patients; non-HDL under 130 mg/dL generally and under 100 mg/dL for higher-risk patients. - Reported screening guidance: for most men in their 40s and 50s, testing every 1–2 years if levels and overall risk are low; with risk factors or on cholesterol medication, testing is reported as more frequent (about every 6–12 months). Summary: Higher LDL and non-HDL readings are reported as being tied to plaque buildup and increased risk of heart attack and stroke, and the article provides typical target ranges for general and higher-risk patients. Screening intervals are presented as depending on individual risk, with more frequent testing reported for people who have risk factors.