The U.S. Food and Drug Administration granted Breakthrough Therapy Designation to IPN60340 given with venetoclax and azacitidine for first-line unfit acute myeloid leukemia, based on early Phase I/II EVICTION trial data. Ipsen plans to discuss Phase II/III development plans with the FDA in the first half of 2026.
McDonald's Canada said it will cut McValue meals from $6 to $5 and keep a small coffee at $1 for at least one year, citing scale with suppliers and franchisee support. The company said menu items and portion sizes on the McValue menu will remain unchanged.
Anthony Pellegrino of Goldstone Financial Group says a rising account balance or portfolio is not the same as a complete retirement plan and emphasizes that retirement readiness involves income, taxes, healthcare, longevity and behavioral factors.
JPMorgan Chase reported $13.0 billion in fourth-quarter profit, down 7% from a year earlier, while revenues rose 7% to $45.8 billion; CEO Jamie Dimon defended Federal Reserve Chair Jerome Powell and cited geopolitical and inflation risks.
Gus Van Sant’s Dead Man's Wire is a 1970s-set docudrama about a man confronting a mortgage company; the review describes it as timely and technically assured while noting it takes liberties with the true story.
Justice Sheilah Martin announced she will retire from the Supreme Court of Canada, with her last day on May 30, after nearly eight years on the bench.
Satellite images from late December 2025 show iceberg A-23A has bright blue surface melt ponds; the iceberg's area has fallen from about 4,000 km² in 1986 to roughly 1,182 km² by January 2026.
Spot silver reached a record $89.05 an ounce and is about 12% higher year-to-date, after finishing 2025 with roughly a 140% gain.
Activists report that more than 2,000 people have died in nationwide protests in Iran, and widespread communications outages have limited independent verification.
Justice Sheilah Martin will leave the Supreme Court of Canada effective May 30, creating a vacancy; she was appointed to the court in 2017 and has focused on Indigenous issues, education and equality.
